Christina M. Astley, MD, ScD is a computational and translational research faculty member in the Divisions of Endocrinology and Computational Epidemiology Lab at Boston Children’s Hospital (BCH), focused on the development of innovative methods to understand individual- and population-level disease dynamics. Her unique background spans endocrinology, epidemiology, inference, and mathematical modeling. Her research has focused on the transmission and control of pandemic disease, and the use of personal medical device (e.g. continuous glucose monitor) and omics data to define disease states (e.g. endocrinopathies, autoimmunity). In conjunction with the BCH Innovation & Digital Health Accelerator, she helped develop and lead analyses of real-time, global health data (OutbreaksNearMe,, Global COVID Trends and Impacts Survey) to inform the COVID-19 pandemic response, including the effectiveness of masking, testing disparities, and characterizing sequelae of infection. She also serves as the pediatric endocrinologist in the BCH Multiple Autoimmunity and Immunodeficiency Clinic.

Christina received her BS in Biological Sciences from Stanford University (Honors with Stanley Falkow), MD from the Harvard-MIT Division of Health Sciences and Technology (Harvard Medical School, Medical Scientist Training Program), and ScD in Epidemiology from the Harvard School of Public Health (thesis advisor Marc Lipsitch). She completed her pediatrics residency in the Boston Combined Residency Program, and pediatric endocrinology fellowship at Boston Children's Hospital (fellowship advisor Joel N. Hirschhorn).


Hiking in the wild with her family, exploring hidden treasures in big and small cities, and attempting to make a gourmet meal out of random ingredients